As IL and many others have pointed out earlier in similar threads, Germany was not (enough) ready for a war against Russia in 41. And Germany should never have attacked Russia before finishing off UK.
And if Germany and Japan was as “alliefied” as UK+US they would have had a much better chance of winning the WW2, conducting different strategies which was not coordinated was a bad choice, but “playing together” would have made a very big difference.