Depending on the Axis positioning, I’d argue for a German Lurch and abondoning of WE.
If Germany is sufficiently strong enough to hold WE and EE while maintaining both Kar and Ukr as deadzones, then great, keep Kar deadzoned and continue your build up (assuming you are still earning something from Afr) and wait for Japan.
But if it is clear you cannot prevent the Allied move to Kar, you need to pull out of WE and shift everything East (or increase your EE stack). Done at the right time this should do a few things for the Axis:
1) Keeps Berlin heavily defended so arm can stay in EE
2) Prevents the Allies from moving to Kar for a few more turns
3) Allows you to trade WE with your superior airforce and pretty much forces either of the Allies to send an inf or two to capture WE, otherwise Germany gets 6 ipc with no defending units present
4) If the Allies land heavy in WE you should either (a) be able to smash them with well over 20 inf, a few rt, and all your arm/planes (b) successfully seperated the UK and US from Russia
The Allies combined can hold off Japan, but if Japan is a 45-50 ipc Monster it becomes hard for Russia to hold off Japan all by herself esp if Germany had been trading with Russia for the first 4-5 rounds and weakened her offensive power.